275,00 € – 625,00 €
A single-domain antibody (sdAb) that specifically and strongly binds to the cytoplasmic domain of murine and rat Synaptotagmin 1 (SYT1).
Synaptotagmin 1 (SYT1) is a member of a protein family consisting of 17 members. Synaptotagmins are single-pass transmembrane proteins containing two calcium-binding domains in their intracellular portion. Synaptotagmin 1 is enriched at the presynaptic boutons on axon terminals, associated with synaptic vesicles, and is implicated in triggering vesicle fusion and neurotransmitter release upon a local increase in calcium concentration.
Our nanobody strongly and specifically binds to the cytosolic portion of mouse and rat SYT1.
Variations: |
|
||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Related Products: | |||||||||||||||||
Clone: | 7D5 | ||||||||||||||||
Host: | Alpaca | ||||||||||||||||
Produced in: | E.coli | ||||||||||||||||
Application: |
IF Note: This product is not recommended for detecting proteins in Western blot, as sdAbs tend to recognize native/folded proteins mainly. |
||||||||||||||||
Dilution: | N/A | ||||||||||||||||
Capacity: | N/A | ||||||||||||||||
Antigen: | - | ||||||||||||||||
Targets: | Synaptotagmin 1 (cytosolic) | ||||||||||||||||
Specificity: | Recognizes the cytosolic domain of rat and mouse Synaptotagmin 1 (other species not tested). | ||||||||||||||||
Formulation: |
DBCO- and Biotin-conjugated sdAbs (1:1 labeling on the C-terminus) are lyophilized from PBS pH 7.4. |
||||||||||||||||
kDa: | 15,5 | ||||||||||||||||
Ext Coef: | 24200 | ||||||||||||||||
Shipping: | Ambient temperature | ||||||||||||||||
Storage: |
Vials containing lyophilized reagent can be stored at 2-8°C for up to 12 months. After reconstitution, store at -80°C for up to 6 months. Working aliquots can be stored at -20°C for up to 4 weeks. For more details, click the Protocols button above and check Reconstitution and Storage. |
||||||||||||||||
Protocols: |
Relevant protocols can be found under the Protocols button above. For additional information, visit our Resources page. |
||||||||||||||||
References: |
|
||||||||||||||||
Notice: | To be used in vitro/ for research only. Non-toxic, non-hazardous, non-infectious. | ||||||||||||||||
Legal terms: | By purchasing this product you agree to our general terms and conditions. |