Immuno-histochemical sections of FFPE Covid-19 infected-Vero cells were kindly provided by Prof- Dr. med. Andreas C. Hocke (Charité -Universitätsmedizin Berlin). Staining with biotinylated sdAb anti-SARS-CoV-2 Nucleocapsid (N3505-Biotin) and 1:100 visulized with ABC Kit HRP (Vector PK-4000). Nuclei have been counterstained with haematoxylin (blue).
250,00 € – 600,00 €
The nucleocapsid (N) protein of SARS-CoV-2 is an abundant RNA-binding protein critical for the packaging of the single-stranded RNA viral genome. Due to its abundance, it is an interesting target for antibody detection in biopsies and tissue. The protein N is also present inside virion particles bound to single-stranded RNA.
Our nanobody binds strongly to protein N of SARS-CoV-2, even under harsh sample treatment conditions, e.g. paraffin-embedded tissue.
|Specificity:||Recognizes the Nucleocapsid protein of SARS-CoV-2 and SARS-CoV-1.|
|Formulation:||DBCO and biotin conjugated sdAbs (1:1 labeling on the c-term.) are lyophilized from PBS pH 7.4. Unconjugated sdAbs are lyophilized from 10 mM KPi pH 6.0,150 mM NaCl, 1 mM EDTA. Reconsitute with 250 µL pure water (unconjugated sdAbs), or with 250 µL 50% glycerol for storage at -80 °C (DBCO-, Biotin-conjugated sdAbs). Use unconjugated sdAbs immediately after reconstitution.|
|Storing:||Vials containing lyophilized protein can be stored at 4°C for up to 6 months. Vials containing reconstituted protein should be stored at -20°C or below.|
|Notice:||To be used in vitro/ for research only. Non-toxic, non-hazardous, non-infectious.|
|Legal terms:||By purchasing this product you agree to our general terms and conditions.|