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Immuno-histochemical sections of FFPE Covid-19 infected-Vero cells were kindly provided by Prof- Dr. med. Andreas C. Hocke (Charité -Universitätsmedizin Berlin). Staining with biotinylated sdAb anti-SARS-CoV-2 Nucleocapsid (N3505-Biotin) and 1:100 visulized with ABC Kit HRP (Vector PK-4000). Nuclei have been counterstained with haematoxylin (blue).

sdAb anti-SARS-CoV-2 Nucleocapsid

Cat No: N3605 Category:

250,00 € – 600,00 €

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The nucleocapsid (N) protein of SARS-CoV-2 is an abundant RNA-binding protein critical for the packaging of the single-stranded RNA viral genome. Due to its abundance, it is an interesting target for antibody detection in biopsies and tissue. The protein N is also present inside virion particles bound to single-stranded RNA.

Our nanobody binds strongly to protein N of SARS-CoV-2, even under harsh sample treatment conditions, e.g. paraffin-embedded tissue.

MSDS
Variations:
Conjugation Amount Cat No.
unconjugated C-terminal Cys 250 μg N3605-250µg
Biotin 250 μg N3605-Biotin
DBCO 250 μg N3605-DBCO
Related Products: -
Clone: 2A7
Host: Alpaca
Produced in: E.coli
Application: IF, IHC
Dilution: N/A
Capacity: N/A
Antigen: SARS-CoV-2 Nucleocapsid
Specificity: Recognizes the Nucleocapsid protein of SARS-CoV-2 and SARS-CoV-1.
Formulation: DBCO and biotin conjugated sdAbs (1:1 labeling on the c-term.) are lyophilized from PBS pH 7.4. Unconjugated sdAbs are lyophilized from 10 mM KPi pH 6.0,150 mM NaCl, 1 mM EDTA. Reconsitute with 250 µL pure water (unconjugated sdAbs), or with 250 µL 50% glycerol for storage at -80 °C (DBCO-, Biotin-conjugated sdAbs). Use unconjugated sdAbs immediately after reconstitution.
kDa: 16.8
Ext Coef: 30098
Shipping: Ambient temperature
Storing: Vials containing lyophilized protein can be stored at 4°C for up to 6 months. Vials containing reconstituted protein should be stored at -20°C or below.
Protocols: -
References: -
Notice: To be used in vitro/ for research only. Non-toxic, non-hazardous, non-infectious.
Legal terms: By purchasing this product you agree to our general terms and conditions.

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