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STED image of indirect immunostaining of PFA fixed mouse brain with FluoTag-X2 anti-PSD95 AbberiorSTAR 635P (cat. no. N3702-Ab635P-L).

sdAb anti-PSD95

Cat No: N3705 Category:

275,00 € – 625,00 €

A single-domain antibody that specifically recognizes mouse and rat PSD95.

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Postsynaptic Density Protein 95 or PSD95 (alternative names: PSD-95, SAP-90 and DLG4) is a member of the MAGUK family, and it plays an essential role in forming a dynamic scaffold at the post-synapses. It functions as an organizing centrum of receptors, ion channels, kinases, and other relevant players in achieving synaptic plasticity and molecular changes during long-term potentiation.

Our nanobody binds selectively and strongly to one of the PDZ domains of PSD95, and it does not bind to either of its close family members, PSD93 or SAP102.

MSDS
Protocols
Reconstitution and Storage
Variations:
Conjugation Amount Cat No. RRID
unconjugated C-terminal Cys 250 μg N3705-250ug AB_3076107
Biotin 250 μg N3705-Biotin AB_3076108
DBCO 250 μg N3705-DBCO AB_3076109
Related Products: -
Clone: 1B2
Host: Alpaca
Produced in: E.coli
Application: IF, IHC
Dilution: N/A
Capacity: N/A
Antigen: -
Targets: PSD95
Specificity: Recognizes PSD95 from mouse and rat (other species not tested).
Formulation: DBCO- and Biotin-conjugated sdAbs (1:1 labeling on the C-terminus) are lyophilized from PBS pH 7.4. Unconjugated sdAbs are lyophilized from 5 mM KPi pH 6.0, 300 mM NaCl, 0.5 mM EDTA pH 6.0. Reconstitute with 250 µL pure deionized water for immediate use or with 250 µL sterile 50% glycerol for storage at -80°C. For more details, click the "Protocols" button above and check "Reconstitution and Storage".
kDa: 15.4
Ext Coef: 24138
Shipping: Ambient temperature
Storing: Vials containing lyophilized reagent can be stored at 2-8°C for up to 12 months. After reconstitution, store at -80°C for up to 6 months. Working aliquots can be stored at -20°C for up to 4 weeks. For more details, click the "Protocols" button above and check "Reconstitution and Storage".
Protocols:

Relevant protocols can be found under the “Protocols” button above. For additional information, visit our Resources page.
References:
  1. Unterauer EM, Shetab Boushehri S, Jevdokimenko K, et al. Spatial proteomics in neurons at single-protein resolution. Cell. 2024;187(7):1785-1800.e16. doi:10.1016/j.cell.2024.02.045 (IF/ICC; DNA-PAINT)
Notice: To be used in vitro/ for research only. Non-toxic, non-hazardous, non-infectious.
Legal terms: By purchasing this product you agree to our general terms and conditions.

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