PSD95 (alternative names: PSD-95 or SAP-90) is a member of the MAGUK family, and it plays an important role in the formation of a dynamic scaffold at the post synapses. It functions as an organizing centrum of receptors, ion channels, kinases, and other relevant players in achieving synaptic plasticity and molecular changes during long-term potentiation.
Our nanobody binds selectively and strongly to one of the PDZ domains of PSD95, and it does not bind to either of its close family members PSD93 or SAP102.
Variations: |
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Related Products: | - | ||||||||||||
Clone: | 1B2 | ||||||||||||
Host: | Alpaca | ||||||||||||
Produced in: | E.coli | ||||||||||||
Application: | IF, IHC | ||||||||||||
Dilution: | N/A | ||||||||||||
Capacity: | N/A | ||||||||||||
Antigen: | - | ||||||||||||
Targets: | PSD95 | ||||||||||||
Specificity: | Recognizes PSD95 from mouse and rat (other species not tested). | ||||||||||||
Formulation: | DBCO and biotin-conjugated sdAbs (1:1 labeling on the c-term.) are lyophilized from PBS pH 7.4. Unconjugated sdAbs are lyophilized from 10 mM KPi pH 6.0,150 mM NaCl, 1 mM EDTA. Reconstitute with 250 µL pure water (unconjugated sdAbs) or with 250 µL 50% glycerol for storage at -80°C (DBCO-, Biotin-conjugated sdAbs). Use unconjugated sdAbs immediately after reconstitution. | ||||||||||||
kDa: | 15.4 | ||||||||||||
Ext Coef: | 24138 | ||||||||||||
Shipping: | Ambient temperature | ||||||||||||
Storing: | Vials containing lyophilized protein can be stored at 4°C for up to 6 months. Vials containing reconstituted protein should be stored at -20°C or below. | ||||||||||||
Protocols: |
You can find protocols on our Resources page |
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References: | - | ||||||||||||
Notice: | To be used in vitro/ for research only. Non-toxic, non-hazardous, non-infectious. | ||||||||||||
Legal terms: | By purchasing this product you agree to our general terms and conditions. |