anti-ALFA Bispecifics

Cat No: N1590 Category:


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Bi-specific single-domain antibodies represent a groundbreaking advancement in the field of immunotherapy and targeted drug delivery. These innovative molecules are engineered to bind simultaneously to two distinct antigens or epitopes, which can be particularly advantageous for complex diseases like cancer and autoimmune disorders. By targeting two different pathological markers at once, these antibodies can enhance the specificity and efficacy of treatments, potentially reducing side effects and improving patient outcomes. For example, in cancer therapy, one part of the bi-specific antibody might bind to a cancer cell marker, while the other targets a molecule on immune cells, thereby directing the immune system to attack the cancer cells more effectively. Similarly, in autoimmune diseases, they can be designed to interfere with specific pathways involved in the disease process, offering a more targeted approach to treatment compared to conventional therapies.

These anti-ALFA/anti-IgG (various subtypes available) bi-specitifics can be used to target monoclonals to ALFA-tagged proteins. By using this modular systems many different combination of primary monoclonals and ALFA-tagged tragets can be assayed without having to create all possbile variants from scratch.

Conjugation Amount Cat No. RRID
msIgG1 250 μg N1590-250ug -
msIgG2a/b 250 μg N1591-250ug -
rbIgG 250 μg N1592-250ug -
Related Products: -
Clone: ALFA 1G5; msIgG1 10A4; msIgG2 14A4; rbIgG 10E10
Host: Alpaca
Produced in: E.coli
Application: ELISA, FACS
Dilution: N/A
Capacity: N/A
Antigen: -
Targets: ALFA/msIgG1, ALFA/msIgG2a/b, ALFA/rbIgG
Specificity: The anti-ALFA sdAb recognizes the ALFA-tag (SRLEEELRRRLTE). Each anti-Mouse IgG, or anti-Rabbit IgG sdAb recognizes either native mouse IgG1, mouse IgG2a, IgG2b, or rbIgG, respectively. The anti-Mouse IgG1 and anti-Mouse IgG2a/b sdAbs do not cross-react with Guinea Pig, Rat, Rabbit, Chicken, Donkey, Goat, Pig, Horse, Cow or Human IgGs. The anti-Rabbit IgG sdAb does not cross-react with Mouse, Guinea Pig, Chicken, Rat, Donkey, Goat, Pig, Horse, Cow or Human IgGs.
Formulation: The sdAbs are lyophilized from PBS pH 7.4. Reconstitute with 250 µL 50% glycerol for storage at -80°C.
kDa: -
Ext Coef: -
Shipping: Ambient temperature
Storing: Vials containing lyophilized protein can be stored at 4°C for upto 6 months. Vials containing reconstituted protein should be stored at -20°C or below.
Protocols: -
References: -
Notice: To be used in vitro/ for research only. Non-toxic, non-hazardous, non-infectious.
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