Glial Fibrillary Acidic Protein (GFAP) belongs to type III intermediate filaments, like vimentin, and is primarily expressed in astrocytes within the central nervous system, making it an important marker for differentiating these cells from neurons and other glial cells during development. Although its precise role in astrocytes remains not fully understood, GFAP plays a crucial role in the structural integrity and maintenance of the blood-brain barrier and is involved in the response to CNS injury and disease. As such, GFAP is widely used as a cellular marker in neurological research.
sdAb anti-GFAP carries one C-terminal ectopic cysteine for further chemical modification.
MSDS
Protocols
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| Related Products: | - | ||||||||||||||||
| Clone: | 1D12 | ||||||||||||||||
| Host: | Alpaca | ||||||||||||||||
| Produced in: | E.coli | ||||||||||||||||
| Application: | IF | ||||||||||||||||
| Dilution: | 1:500 | ||||||||||||||||
| Capacity: | N/A | ||||||||||||||||
| Antigen: | - | ||||||||||||||||
| Targets: | GFAP | ||||||||||||||||
| Specificity: | murine GFAP: all isoforms | ||||||||||||||||
| Formulation: | DBCO and biotin conjugated sdAbs (1:1 labeling on the c-term.) are lyophilized from PBS pH 7.4. Unconjugated sdAbs are lyohilized from 10 mM KPi,150 mM NaCl, 1 mM EDTA pH 6.0. Reconsitute with 250 µL pure water for immidate use or with 250 µL 50% glycerol for storage at -80°C. | ||||||||||||||||
| kDa: | 15.2 | ||||||||||||||||
| Ext Coef: | 21618 | ||||||||||||||||
| Shipping: | Ambient temperature | ||||||||||||||||
| Storing: | Vials containing lyophilized protein can be stored at 4°C for up to 6 months. Vials containing reconstituted protein should be stored at -20°C or below. | ||||||||||||||||
| Protocols: | - | ||||||||||||||||
| References: | - | ||||||||||||||||
| Notice: | To be used in vitro/ for research only. Non-toxic, non-hazardous, non-infectious. | ||||||||||||||||
| Legal terms: | By purchasing this product you agree to our general terms and conditions. |
