Ubiquitin K48 Selector is based on a high-affinity single-domain antibody (sdAb) that is covalently immobilized on 4% cross-linked agarose beads. The innovative, oriented and selective attachment via a flexible linker guarantees a high accessibility of the sdAbs and largely eliminates batch-to-batch variations. Due to the single-chain nature of sdAbs and their covalent attachment, no "leakage" of light and heavy chains from IgGs is observed during elution with SDS sample buffer. The Ubiquitin K48 Selector specifically recognizes the lysine 48 linkages in polyubiquitin and will only precipitate polyubiquitin chains when this particular linkage is present.
Recognizes K48-linkage of polyubiquitins
Support: 4% cross-linked agarose beads
Capacity: Resin contains ≥ 150 µM functional sdAbs
Formulation: 50% slurry in 20% ethanol / PBS
Recommended for: Immunoprecipitation, Mass Spectrometry
|Product name||Resin||Amount||Net price (€)||Catalog Number||Order at|
|Ubiquitin K48 Selector||4% CL agarose||2000 µl slurry for up to 100 reactions||see webshop||N1810|
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