For biochemical application, we offer single-domain antibody-based reagents with supperior features.
Most of our single-domain antibody-based affinity tools resist high salt, up to 60 °C or 4 M urea without loosing their binding capability. Consult us or refer to the product data sheet for specific details.
Our high capacity SelectorResins are decorated with a high concentration of Tags. This is not only good for pull-down of highly diluted target proteins, but also helps you to minimize bead consumption.
Our SelectorResins contain covalently coupled sdAb fragments. This effectively prevents the massive light/heavy chain contaminations common to IP experiments using conventional IgGs.
Our SelectorResins contain high-affinity Tags coupled in fixed orientation via defined linkers. Compared to random immobilization strategies, this ensures an optimal accessibility of active Tags.
Our small, monovalent Tags are ideally suited for quantitative Western Blots, as they bypass the intrinsic quantification issues caused by the heterogeneity, large size and divalent nature of IgGs.
Our current product lines are based on recombinant single-domain antibodies (sdAbs) derived from llamas or alpacas. This type of affinity Tags (also known as “Nanobodies”; trademark owned by Ablynx) provides significant advantages over conventional IgG molecules. All of our Tags are produced in-house. They are highly specific with affinities tailored for a wide range of applications.