This anti-Sars-CoV-2 Spike protein S1 nanobody was developed by the team of Alejandro Rojas-Fernandez at the Institute of Medicine from the Universidad Austral de Chile. We acquired the exclusive license to produce this nanobody and make it available for research and development purposes. The FluoTag-Q anti-SARS-CoV-2 S1 is based on the W25 clone, which has a sub-nanomolar affinity for the SARS-CoV-2 S1 protein receptor binding domain (RBD) and can neutralize infections as it efficiently competes with ACE-2 receptor binding.
Datasheet: Download PDF
RBD of S1 protein from SARS-CoV-2
Produced in: E. coli
Concentration: 5 µM protein, 5 µM fluorophore
Recommended dilution for IF/ ICC: 1:500
Available conjugates: Atto 488, AZDye™ 568 (Alexa Fluor® 568 C5 Maleimide equivalent), Alexa Fluor® 647, Abberior® Star 580, Abberior® Star 635P, DBCO and biotin. For other fluorophores or conjugates please contact us.
Potent neutralization of clinical isolates of SARS-CoV-2 D614 and G614 variants by a monomeric, sub-nanomolar affinity Nanobody